Gene Expression Profiling, Genotyping, and Genomic Analysis

USC CIRM ASCEND Shared Resource Laboratory (SRL)

The CIRM ASCEND (Advancing Stem Cell Education and Novel Discoveries) Shared Resource Laboratory (SRL) provides expertise in stem cell and organoid models, coupled with state-of-the-art single cell and spatial sequencing technologies, and linked training courses to the broad California research community. It welcomes students and collaborators from the higher education systems, high school students, and all areas of biotechnology. The CIRM ASCEND SRL is part of a network of SRLs funded by CIRM that are aimed to democratize science by making challenging models, experiments, and tools accessible. For a full set of services provided in California, visit the CIRM website at https://www.cirm.ca.gov.

Eli and Edythe Broad CIRM Center (BCC) for Regenerative Medicine and Stem Cell Research

Keck School of Medicine University of Southern California
1975 Zonal Ave, Los Angeles, CA 90033

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Keck Genomic Platform

The Keck Genomics Platform (KGP CORE) provides high-throughput industry-standard next-generation sequencing services to the University of Southern California and its collaborators. KGP utilizes Illumina high-throughput next generation sequencers, such as NovaSeq 6000 and Miseq, to offer comprehensive data analysis, customized pipelines, and secure data management. KGP allows for collaborative research and genomic innovation offering comprehensive services from sample processing to data analysis.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

323-442-1100

Website

Genome Modification Facility

The Genome Modification Facility produces transgenic and knockout mice and rats, and increases the use of mouse and rat technology through education and consultation to the scientific research community. The facility also offers CRISPR/Cas9-mediated gene editing in mice. Ancillary services include in vitro fertilization, re-derivation of mouse strains, and cryopreservation of sperm and embryos, with the overall goal of offering state-of-the art services for the manipulation of mouse and rat genomes.

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC
1425 San Pablo Street, BCC 205
Los Angeles, CA 90033-9080
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Bioinformatics Core

Bioinformatics is an interdisciplinary science that brings together approaches from biology, genomics, biostatistics, computer science, mathematics, medicine and health. At a basic functional level, bioinformatics is the application of computing tools to biological data to make it understandable. Thus, bioinformatics helps to gather, store, organize, and analyze large volumes of data, or big data, whereby such data can be transformed into interpretable pieces of information. When applied to gerontology research, bioinformatics incorporates the investigator’s goal of using computational tools and resources to answer research questions aimed at improving human health across the lifespan, and into older ages.

3715 McClintock Avenue Los Angeles CA 90089
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Aging Murine Phenotyping Core

We collaborate in scholarship and service to improve how people live and age, now and for generations to come. As the first, largest and most renowned School of Gerontology, we pioneered the study of aging. Today, we continue to boldly reimagine the future, break new ground and launch students into meaningful careers.

Services include: Inflammatory cytokines/chemokines, Alzheimer-related markers (Amyloid beta, phospho-tau), Metabolic biomarkers (insulin, leptin, adiponectin, etc), Human and mouse IGF-I & IGFBPs (1, 2 3), GH, etc., Mitochondrial derived peptides (MDPs): humanin, SHLP2, MOTS- C, etc, and new assay development.

USC Leonard Davis School of Gerontology, 3715 McClintock Ave, GER B1B
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Molecular Genomics Core

The Molecular Genomics Core (MGC) provides services for industry-standard and state-of-the-art molecular and genomic assays in support of USC investigators working across the continuum of basic, translational, clinical and population sciences.

Equipment and services include: Next-generation sequencing, sc-RNA, 10X Genomics, ATAC-seq, genotyping, methylation arrays, genotyping, Illumina

Health Sciences Campus
USC Norris Comprehensive Cancer Center
Los Angeles, CA 90033
Website