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Gene Expression Profiling, Genotyping, and Genomic Analysis

Molecular Genomics Core

The Molecular Genomics Core (MGC) provides services for industry-standard and state-of-the-art molecular and genomic assays in support of USC investigators working across the continuum of basic, translational, clinical and population sciences.

Equipment and services include: Next-generation sequencing, sc-RNA, 10X Genomics, ATAC-seq, genotyping, methylation arrays, genotyping, Illumina

Health Sciences Campus
USC Norris Comprehensive Cancer Center
Los Angeles, CA 90033
Website

USC Libraries Bioinformatics Service

The USC Libraries offers a university-wide bioinformatics support service for all faculty, students, and researchers. We provide research consultation and training, bioinformatics software, collaborative data analysis, and computing resources, catering to a wide range of bioinformatics tasks, including experimental design, statistical analysis of high-throughput genomic data, comprehensive functional analyses, advanced literature study, public genomic data mining, etc. We also provide bioinformatics support for grant applications.

UPC Office
CEM 202
814 Bloom Walk

HSC Office
Norris Medical Library RM203
2003 Zonal Ave
Website

USC Genome Core

The USC Genome Core is located on the UPC campus, and it offers Next-Generation Sequencing services to all USC researchers. Equipment includes: Illumina HiSeq 2500, Illumina NextSeq 550, and Ion Torrent PGM, plus all ancillary equipment needed for sample and library QC (Bioanalyzer, qPCR, etc.). Services include: NGS sequencing, library preparation, sample and library QC, and consultation.

University Park Campus
Center for Electron Microscopy & Microanalysis
814 Bloom Walk, CEM203
Los Angeles, CA 90089
Website

Translational Research Laboratory

The core mission of the USC School of Pharmacy Translational Research Laboratory (TRLab), located in 13laboratory spaces of the Pharmaceutical Sciences Center, has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the School of Pharmacy and at USC.

Equipment and services include: The TRLab is equipped with over 80 specialized instruments in the applications of: 1) Sample Processing, 2) Cell and Immunobiology, 3) Flow Cytometry, 4) Imaging, 5) Molecular Analysis, 6) Molecular Biology and 7) RNA/DNA Sequencing.

Health Sciences Campus
Pharmaceutical Sciences Center
Website

Lentiviral Core Laboratory

The USC School of Pharmacy Lentiviral Laboratory provides services for production of small-scale lentiviral stocks for delivery and expression of transgenes or shRNA of interest. The engineered lentiviral constructs are either provided by the end-users or produced in the lab according to the needs of the customers. We also help in stable cell line generation and characterization.

Website

Vector Core

The Vector Core provides researchers with state of the art technology, facilities, support staff and services and a broad range of resources. Services include: assistance in the design and construction viral vectors and viral particles for gene-modified in vitro/in vivo studies. The core also provides consulting services to identify researcher gene transfer needs, determine the best way to produce gene-modified cells, and to assist in experimental troubleshooting. Equipment includes: Hollow fiber tangential flow filtration (TFF) columns (Spectrum Labs) to filter and concentrate lentiviral vectors up to 100 fold with high recovery (>90%).

Children’s Hospital Los Angles, CHLA
Smith Research Tower
4546 Sunset Blvd., Rm 405
Los Angeles, CA 90027

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Research Initiatives and Infrastructure
Third Floor, 3720 Flower St, Los Angeles, CA 90007
rii@usc.edu

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