Gene Expression Profiling, Genotyping, and Genomic Analysis

Genome Modification Facility

The Genome Modification Facility produces transgenic and knockout mice and rats, and increases the use of mouse and rat technology through education and consultation to the scientific research community. The facility also offers CRISPR/Cas9-mediated gene editing in mice. Ancillary services include in vitro fertilization, re-derivation of mouse strains, and cryopreservation of sperm and embryos, with the overall goal of offering state-of-the art services for the manipulation of mouse and rat genomes.

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC
1425 San Pablo Street, BCC 205
Los Angeles, CA 90033-9080
Website

Bioinformatics Core

Bioinformatics is an interdisciplinary science that brings together approaches from biology, genomics, biostatistics, computer science, mathematics, medicine and health. At a basic functional level, bioinformatics is the application of computing tools to biological data to make it understandable. Thus, bioinformatics helps to gather, store, organize, and analyze large volumes of data, or big data, whereby such data can be transformed into interpretable pieces of information. When applied to gerontology research, bioinformatics incorporates the investigator’s goal of using computational tools and resources to answer research questions aimed at improving human health across the lifespan, and into older ages.

3715 McClintock Avenue Los Angeles CA 90089
Website

Aging Murine Phenotyping Core

We collaborate in scholarship and service to improve how people live and age, now and for generations to come. As the first, largest and most renowned School of Gerontology, we pioneered the study of aging. Today, we continue to boldly reimagine the future, break new ground and launch students into meaningful careers.

Services include: Inflammatory cytokines/chemokines, Alzheimer-related markers (Amyloid beta, phospho-tau), Metabolic biomarkers (insulin, leptin, adiponectin, etc), Human and mouse IGF-I & IGFBPs (1, 2 3), GH, etc., Mitochondrial derived peptides (MDPs): humanin, SHLP2, MOTS- C, etc, and new assay development.

USC Leonard Davis School of Gerontology, 3715 McClintock Ave, GER B1B
Website

Molecular Genomics Core

The Molecular Genomics Core (MGC) provides services for industry-standard and state-of-the-art molecular and genomic assays in support of USC investigators working across the continuum of basic, translational, clinical and population sciences.

Equipment and services include: Next-generation sequencing, sc-RNA, 10X Genomics, ATAC-seq, genotyping, methylation arrays, genotyping, Illumina

Health Sciences Campus
USC Norris Comprehensive Cancer Center
Los Angeles, CA 90033
Website

USC Libraries Bioinformatics Service

The USC Libraries offers a university-wide bioinformatics support service for all faculty, students, and researchers. We provide research consultation and training, bioinformatics software, collaborative data analysis, and computing resources, catering to a wide range of bioinformatics tasks, including experimental design, statistical analysis of high-throughput genomic data, comprehensive functional analyses, advanced literature study, public genomic data mining, etc. We also provide bioinformatics support for grant applications.

UPC Office
CEM 202
814 Bloom Walk

HSC Office
Norris Medical Library RM203
2003 Zonal Ave
Website

USC Genome Core

The USC Genome Core is located on the UPC campus, and it offers Next-Generation Sequencing services to all USC researchers. Equipment includes: Illumina HiSeq 2500, Illumina NextSeq 550, and Ion Torrent PGM, plus all ancillary equipment needed for sample and library QC (Bioanalyzer, qPCR, etc.). Services include: NGS sequencing, library preparation, sample and library QC, and consultation.

University Park Campus
Center for Electron Microscopy & Microanalysis
814 Bloom Walk, CEM203
Los Angeles, CA 90089
Website