Plasma Laboratory for Atmosphere, Solid Earth, and Marine Analyses
Equipment and services: Neptune MC-ICPMS, Agilent 8900 QQQ-ICPMS, Agilent 5110 ICP-OES, Mercury Analyzer NIC MA-3000,
ZHS 320
Proteomics and Spectroscopy
Center for Peptide and Protein Engineering
The USC Center for Peptide and Protein Engineering (CPPE) aims to put USC in a position of undisputed leadership in peptide and protein science by creating functional peptides and proteins as imaging agents, diagnostics and therapies. This core laboratory is housed in the Michelson Center for Convergent Biosciences and serves the USC Community to generate new peptide and protein tools. New technology advances in several fields now provide the foundation for high-throughput molecular engineering—creating new peptides and antibody-like proteins that bind specific targets on a genomic scale.
Equipment and services include: A la carte and comprehensive peptide synthesis and purification services for the USC and general community. End-to-end production of peptides includes: assistance in peptide design, Fmoc-based solid-phase peptide synthesis, peptide purification, conformation of peptide identity by mass spectrometry, and assessment of purity by reverse-phase HPLC. Peptide synthesis is performed on a Biotage Syro I Multi-Peptide Synthesizer (supported by a grant from the USC Core Instrumentation Fund) at 50 μmol scale up to 20 amino acids. Peptide purification is performed via Biotage reverse-phase flash chromatography and/or reverse-phase HPLC chromatography using Agilent HPLC and LCMS equipment.
2nd floor
USC Michelson Center for Convergent Bioscience
MCB 267
Nanobiophysics Core
The Center of Excellence in NanoBiophysics supports faculty and students across the university in the study of molecular nano-assembly, structures and functions. Housed in the Dornsife College, the Center is used by research programs in structural biology, nanotechnology, anomedicine, molecular biology, biochemistry, and materials sciences.
3616 Trousdale Parkway
AHF B15
Los Angeles, CA 90089
Mass Spectrometry Core
The Mass Spectrometry Core at USC Mann School of Pharmacy serves the scientific research community at USC as well as external collaborators. Our Core is equipped with state-of-the-art instruments for imaging mass spectrometry (IMS), high-throughput screening, and quantitative metabolomic and proteomics. Our Core is dedicated to actively collaborate with internal and external research groups in providing comprehensive service in MALDI imaging and high-throughput screening of small molecules, peptides, and proteins using mass spectrometry.
University of Southern California
1985 Zonal Avenue
Los Angeles, CA 90089-9121
Website
Proteomics Core
Located at the CHLA Saban Research Institute, the Proteomics Facility utilizes proteomics with advanced mass spectrometry to investigate protein functions and roles in disease. Equipment & services include: poteomics and mass spectrometry services utilizing Eksigent nanoLC-2D and Thermo LTQ Orbitrap XL. Proteomics software includes Thermo Bioworks and Protein Scaffold Software.
Children’s Hospital Los Angeles, CHLA
Smith Research Tower
4546 Sunset Blvd., Rm 106, MS#64
Los Angeles, CA 90027
Chemistry Instrumentation Facility
Instruments at the Chemistry Instrumentation Facility are maintained and supervised by technical personnel as departmental facilities.
Equipment and services include: Bruker Vertex 80 FTIR spectrometer with vacuum capability; Cary 14 UV-Visible spectrometer; Bruker EPR spectrometer; Jasco temperature-controlled digital polarimeter; Applied Biosystems MALDI mass spectrometer; Bruker APEX diffractometer with a CCD area detector for single-crystal applications; Rigaku Ultima IV powder/thin film diffractometer; Horiba XploRA Raman Microscope System with low temperature cell attachment and a Horiba NanoLog Spectrofluorometer System with both visible and near-IR detectors; as well as a wide variety of specialized laser spectroscopy equipment, surface analysis instruments, mass-selective gas chromatography, mass-selective HPLC, and scanning probe microscopes.
University Park Campus
USC Department of Chemistry
3620 McClintock Avenue, SGM 418
Los Angeles, CA 90033
Website