• Skip to primary navigation
  • Skip to main content

Research Initiatives and Infrastructure

University of Southern CaliforniaResearch and Innovation
  • Funding
  • Limited Submissions
  • Shared Resources
  • Training
  • Announcements
  • Contact
You are here: Home / Shared Resources / Center for Peptide and Protein Engineering

Center for Peptide and Protein Engineering

The USC Center for Peptide and Protein Engineering (CPPE) aims to put USC in a position of undisputed leadership in peptide and protein science by creating functional peptides and proteins as imaging agents, diagnostics and therapies. This core laboratory is housed in the Michelson Center for Convergent Biosciences and serves the USC Community to generate new peptide and protein tools. New technology advances in several fields now provide the foundation for high-throughput molecular engineering—creating new peptides and antibody-like proteins that bind specific targets on a genomic scale.

Equipment and services include: A la carte and comprehensive peptide synthesis and purification services for the USC and general community. End-to-end production of peptides includes: assistance in peptide design, Fmoc-based solid-phase peptide synthesis, peptide purification, conformation of peptide identity by mass spectrometry, and assessment of purity by reverse-phase HPLC. Peptide synthesis is performed on a Biotage Syro I Multi-Peptide Synthesizer (supported by a grant from the USC Core Instrumentation Fund) at 50 μmol scale up to 20 amino acids. Peptide purification is performed via Biotage reverse-phase flash chromatography and/or reverse-phase HPLC chromatography using Agilent HPLC and LCMS equipment.

2nd floor
USC Michelson Center for Convergent Bioscience
MCB 267

Website

Research Initiatives and Infrastructure
Third Floor, 3720 Flower St, Los Angeles, CA 90007
rii@usc.edu

University of Southern California   Content managed by RII
  • Privacy Notice - Notice of Non-Discrimination