Biomarkers, Cell Culture, and Analysis

Agilent Center of Excellence in Biomolecular Characterization

The Agilent Center of Excellence in Biomolecular Characterization was established as a partnership between USC and Agilent technologies with the goal to converge researchers across science and engineering to work together on multidisciplinary approaches for the development of new drugs, diagnostics, and medical devices. The center features first-in-class research instruments ranging from advanced mass spectrometry, chromatography, robotic high-throughput reaction screening, genomics, and optical characterization.

Located at Michelson since 2018

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The Research Center for Liver Disease Cell and Tissue Imaging Core

The USC Research Center for Liver Diseases (RCLD) was originally founded in March 1995 and has been continuously funded by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK P30 DK048522) for four consecutive 5-year cycles through 2/21. Dr. Neil Kaplowitz is the interim Director.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

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The Research Center for Liver Disease Liver Histology(LH) Core

The Liver Histology Core provides basic histology services to the members of the Research Center for Liver Disease members. We do processing, sectioning and staining for animal tissues of formalin fixed specimens, which need to be submitted in 70% alcohol. (We can do processing and embedding of such tissues for nonmember investigators, but not sectioning.) We also provide frozen sectioning of animal tissue for our members only.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

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Workforce Development Core

This core group provides expertise in education, training and career development with special focus on research in diverse populations. Their broad target audience includes career clinical researchers, clinicians, research staff, clinical partners and community members. Workforce Development’s various educational offerings is provided in various formats emphasizing topics in clinical translational research methodology, team science, community-engaged research, research in diverse populations, research ethics, use of digital tools in research, and mentorship.

University of Southern California
2250 Alcazar Street, CSC 200
Los Angeles, CA 90033

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Translational Research in Vivo Core

Welcome to the Translational Research In Vivo Core Facility, a center dedicated to state-of-the-art research. The facility has more than 12,000 sq. ft. and includes dedicated procedure rooms. Two full-time technicians are available to assist researchers with procedures and equipment operation. A third technician is available to process tissue for histological analysis.

SC Ginsburg Institute for Biomedical Therapeutics

Keck School of Medicine University of Southern California
1450 San Pablo Street, Room 6500

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Center for Peptide and Protein Engineering

The USC Center for Peptide and Protein Engineering (CPPE) aims to put USC in a position of undisputed leadership in peptide and protein science by creating functional peptides and proteins as imaging agents, diagnostics and therapies. This core laboratory is housed in the Michelson Center for Convergent Biosciences and serves the USC Community to generate new peptide and protein tools. New technology advances in several fields now provide the foundation for high-throughput molecular engineering—creating new peptides and antibody-like proteins that bind specific targets on a genomic scale.

Equipment and services include: A la carte and comprehensive peptide synthesis and purification services for the USC and general community. End-to-end production of peptides includes: assistance in peptide design, Fmoc-based solid-phase peptide synthesis, peptide purification, conformation of peptide identity by mass spectrometry, and assessment of purity by reverse-phase HPLC. Peptide synthesis is performed on a Biotage Syro I Multi-Peptide Synthesizer (supported by a grant from the USC Core Instrumentation Fund) at 50 μmol scale up to 20 amino acids. Peptide purification is performed via Biotage reverse-phase flash chromatography and/or reverse-phase HPLC chromatography using Agilent HPLC and LCMS equipment.

2nd floor
USC Michelson Center for Convergent Bioscience
MCB 267

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