Health Sciences Campus

Center for Auditory and Vestibular Exploration (CAVE)

The Center for Auditory and Vestibular Exploration (CAVE) is a hub of core research facilities within the Caruso Department of Otolaryngology—Head & Neck Surgery. Dedicated to advancing the science of hearing and balance, CAVE offers cutting‑edge infrastructure and expertise for conducting auditory and vestibular research in both human subjects and animal models. Facilities and services include sound‑ and vibration‑isolated booths for auditory experiments, state‑of‑the‑art systems for measuring auditory and vestibular evoked potentials, noise‑exposure facilities, acoustic‑calibration and otoacoustic‑emission facilities.

Address:
Zilkha Neurogenetic Institute
1501 San Pablo St, Los Angeles, CA 90033
ZNI 423B
Website

High throughput screening and liquid handling core

The High Throughput Screening and Liquid Handling (HTS) Core is equipped with advanced automation platforms, including the Echo 650 and Biomek i5 (Beckman), integrated with a centrifuge, temperature controller, and mixer. These systems enable fully automated, high-throughput small molecule screening and liquid handling.

The HTS Core maintains in-house compound libraries comprising:

FDA-approved drugs
Epigenetic modulators
Preclinical compounds
Nucleoside analogs

We support translational research for all USC schools, with a focus on therapeutic development and therapeutic target validation. Our services include: 1) High throughput drug screen, 2) Automated and contactless drug dispensing, 3) High-throughput liquid handling for molecular biology applications; and 4) Assay development and optimization.

Health Sciences Campus
USC Norris Cancer Center
1440 Biggy Street., NOR5838
Los Angeles, CA 90033

Website: https://sites.usc.edu/hts/

USC CIRM ASCEND Shared Resource Laboratory (SRL)

The CIRM ASCEND (Advancing Stem Cell Education and Novel Discoveries) Shared Resource Laboratory (SRL) provides expertise in stem cell and organoid models, coupled with state-of-the-art single cell and spatial sequencing technologies, and linked training courses to the broad California research community. It welcomes students and collaborators from the higher education systems, high school students, and all areas of biotechnology. The CIRM ASCEND SRL is part of a network of SRLs funded by CIRM that are aimed to democratize science by making challenging models, experiments, and tools accessible. For a full set of services provided in California, visit the CIRM website at https://www.cirm.ca.gov.

Eli and Edythe Broad CIRM Center (BCC) for Regenerative Medicine and Stem Cell Research

Keck School of Medicine University of Southern California
1975 Zonal Ave, Los Angeles, CA 90033

Website

Keck Genomic Platform

The Keck Genomics Platform (KGP CORE) provides high-throughput industry-standard next-generation sequencing services to the University of Southern California and its collaborators. KGP utilizes Illumina high-throughput next generation sequencers, such as NovaSeq 6000 and Miseq, to offer comprehensive data analysis, customized pipelines, and secure data management. KGP allows for collaborative research and genomic innovation offering comprehensive services from sample processing to data analysis.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

323-442-1100

Website

Medicinal Chemistry Core(MCC)

Drug Design and Discovery, Medicinal chemistry, Organic Synthesis
Equipment and Services: Organic Synthesis, Drug Design, ADME, Reaction Microwave, CombiFlash NextGen 300+ Automated Flash Chromatography System, ACCQ Prep HP 150

School of Pharmacy-B-4

Website

The Research Center for Liver Disease Cell and Tissue Imaging Core

The USC Research Center for Liver Diseases (RCLD) was originally founded in March 1995 and has been continuously funded by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK P30 DK048522) for four consecutive 5-year cycles through 2/21. Dr. Neil Kaplowitz is the interim Director.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

Website