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Health Sciences Campus

Data Science Core

The mission of the Data Science Core (DSC) of the USC Norris Comprehensive Cancer Center (USC Norris) is to provide integrated state-of-the-art biostatistics and informatics support to USC Norris investigators working on all aspects of cancer research from basic science to translational and clinical studies, and cancer etiology to cancer control. The Data Science Core members work with USC Norris investigators on the planning, design, conduct, analysis, and reporting of cancer research studies. Core members also play a key role in clinical trials protocol review and study monitoring at USC Norris.

1441 Eastlake Ave.
Los Angeles, CA 90033


Website

The Research Center for Liver Disease Cell Separation and Culture(CSC) core

The combined Cell Separation and Culture Core provides two major types of services: 1) cell separation to allow functional analysis of different cell types; and 2) isolation and culture of primary hepatocytes from normal and diseased rodents. Some of the additional services they provide include: 1) 4-8 parameter flow cytometric analyses by BD FACSCalibur and BD FACSVerse cell analyzers; 2) Positive or negative cell separation by Miltenyi AutoMACS Pro instrument. This Core is only open to the Research Center for Liver Disease members.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

323-442-1100

Website

Genome Modification Facility

The Genome Modification Facility produces transgenic and knockout mice and rats, and increases the use of mouse and rat technology through education and consultation to the scientific research community. The facility also offers CRISPR/Cas9-mediated gene editing in mice. Ancillary services include in vitro fertilization, re-derivation of mouse strains, and cryopreservation of sperm and embryos, with the overall goal of offering state-of-the art services for the manipulation of mouse and rat genomes.

Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC
1425 San Pablo Street, BCC 205
Los Angeles, CA 90033-9080
Website

Animal Core

The Animal Core is the center’s scientific hub for catalyzing research on in vivo genetic analysis and synergism between alcohol and risk factors for the pathogenesis of alcoholic liver and pancreatic diseases (ALPD) by investigators within and outside of the center.

Models Provided by the Animal Core: Mouse iG-Std Model, Mouse iG-OF (overfeeding) produces synergistic steatohepatitis by alcohol and obesity, Hybrid HCFD+Alc Model, Hybrid HCFD+Alc+Binge Model, and Rat iG-Std,

1975 Zonal Ave, Los Angeles, CA 90033

323-442-1100


Website

Molecular Genomics Core

The Molecular Genomics Core (MGC) provides services for industry-standard and state-of-the-art molecular and genomic assays in support of USC investigators working across the continuum of basic, translational, clinical and population sciences.

Equipment and services include: Next-generation sequencing, sc-RNA, 10X Genomics, ATAC-seq, genotyping, methylation arrays, genotyping, Illumina

Health Sciences Campus
USC Norris Comprehensive Cancer Center
Los Angeles, CA 90033
Website

4D Quantitative Imaging Lab

4D Quantitative Imaging Lab provides state of the art digital image processing and quantitation. Services and training opportunities include image segmentation, volumetrics, image reformation, visualization, imaging informatics, 3D model generation, and 3D printing. The lab includes workstations configured for anatomical segmentation with research and clinical software installed. Services include DICOM transfer, DICOM anonymization, image/video creation for publication/presentation, and 3D printing.

Equipment and services include: 3 image segmentation workstations with access to Synapse, Synapse 3D, Vitrea Enterprise Server, MIM Software, and Cerner. Form Labs Form 3B Resin 3D printer Vitrea version 7.14 stand alone workstation

Health Sciences Campus
Keck Hospital of USC
KMC B112
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Research Initiatives and Infrastructure
Third Floor, 3720 Flower St, Los Angeles, CA 90007
rii@usc.edu

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