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Recurring Limited Submissions

(CLOSED) The G. Harold and Leila Y. Mathers Foundation Grants – Fall Cycle 2025

Slots: Universities/Institutions are limited to three applications per cycle.

One application per cycle per investigator.

Deadlines

Internal Deadline: Friday, July 18th, 2025, 5pm PT Closed.

Registration Deadline: Friday, September 19, 2025, 5pm PST

LOI: October 3rd, 2025, 5pm PST

Invited Proposals: December 12, 2025 5pm PST

Award Information

Award Type: Grant for basic science, ideally with potential translational applications

Award Amount: Up to $700,000 over three years. IDC cannot exceed 10%. 

Mathers considers the budget request with these factors in mind: the number of researchers and their training; the type of model being used for experiments (mouse, drosophila, c. elegans, etc.); supplies required for experiments; genetic sequencing or other outsourced services, test setup development, etc. The grant does not fund lab equipment.

Who May Serve as PI: Faculty.

Link to Award: http://www.mathersfoundation.org/

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here:

RII-Limited-Submission-Application-Template.

Materials to submit include:

  • (1) Two-Page Proposal Summary (1” margins; single-spaced; font type: Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose/Additional Information:

  • Examples of current research areas supported: immunology, microbiome, structural biology, cellular physiology, cancer biology, genetics, genomics, microbiology and infectious diseases, stem cell biology, and neuroscience. 
  • Research areas NOT supported: Plant biology, oceanography, space exploration, global warming, medical imaging technology, and electrical engineering technology development, research conducted in human subjects, clinical trials, drug discovery.  
  • Requests for funding previously federally supported research and/or applications pending federal approval will not be accorded priority consideration.
  • Mathers reviewers look for innovative, novel proposals, which have scientific merit with an established published proof of concept, and which may not be fundable at the federal level.  

(CLOSED) ADA Pathway to Stop Diabetes: Initiator Awards

Slots: ADA will accept up to two (2) nominations per institution with one (1) nomination spanning basic through preclinical research and one (1) nomination spanning clinical through public health research. 

Each nomination can be for either of the Pathway Program Award types: Initiator or Accelerator. Please be aware that if an institution nominates two (2) applicants with proposed projects covering the same phase of research (i.e. basic through preclinical research studies), one of the submitted applications will be administratively disqualified from consideration for funding.

Deadlines

Internal Deadline: Friday, May 23rd, 2025Closed.

LOI: N/A

External Deadline: Wednesday, July 23rd, 2025

Award Information

Award Type: Grant

Anticipated Award Amount: Up to $100,000 year in Phase 1, up to $325,000/year in Phase 2. Applicants may request up to seven (7) years of combined funding support for phases one and two. The proposed project budget should not exceed the maximum total budget up to $1,625,000 USD.

Who May Serve as Applicant: Applicants must currently be in research training positions (i.e. post-doctoral fellowships, research fellowships) and can have no more than seven (7) years of training since their doctoral degree.

Initiator award recipients cannot concurrently hold an NIH K99/R00 grant. All other Career Development awards are allowable (unless holding of concurrent awards is prohibited by the other granting agency).

Candidate’s must hold a full-time appointment at their sponsoring institution. Rare exceptions to full- time positions may be granted on a case-by-case basis and must be pre-approved by ADA Research Programs staff prior to application submission.

Applicants must hold a MD, PhD, DMD, DO, PharmD, DVM or an equivalent health- or science-related degree.

Applicant fellowship positions must be at university-affiliated institutions or other non-profit research institutions within the United States and U.S. possessions.

To assure continued excellence and diversity among applicants and awardees, the Association welcomes applications from all qualified individuals and strongly encourages applications from persons with diverse backgrounds, including minority groups that are underrepresented in biomedical research.

Individuals must have permission to work within the U.S., either as U.S. citizens or permanent residents, or with appropriate work visas/permits. Institutional confirmation of permission to work within the U.S. will be required at the time of application submission.

Link to Award: https://professional.diabetes.org/research-grants/current-funding-opportunities-pathway-stop-diabetes

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

  • (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose

The Pathway to Stop Diabetes® Initiator award is designed to support early career researchers who have distinguished themselves during their research training as exceptionally talented and promising research investigators with a high likelihood of establishing successful, independent research programs and making seminal contributions in diabetes research.

These awards are highly competitive and intended to support particularly innovative and transformational ideas that have the potential to have an exceptional impact in diabetes with an emphasis on the investigator’s potential to significantly transform diabetes through research (‘moving the needle’) to improve the lives of people with diabetes. These awards provide salary and research support for applicants during late stages of mentored training through establishment as independent research faculty.

If funded, the Principal Investigator must agree to devote at least 75% of their total time and overall effort towards research. This percentage includes time dedicated to the Association-funded grant in addition to grants supported by other funding agencies. Please note that during the award’s duration,

the Principal Investigator must commit between 75-100% effort towards the Association funded project in phase one and between 50-75% effort towards the Association funded project in phase two.

Initiator awards will provide two (2) distinct phases of research support. Applicants may request up to seven (7) years of combined funding support for phases one and two. The proposed project budget should not exceed the maximum total budget up to $1,625,000 USD.

  • Phase One: During phase one, applicants may request up to $100,000 USD per year (including 10% indirect costs) for up to two (2) years for mentored research training to allow investigators to complete on-going research, publish results, receive additional training, and develop independent research plans.

Phase two support will be approved by the ADA Research Programs team contingent upon adequate progress in phase one, as well as the receipt and approval of documentation verifying that:

  1. The candidate has obtained a faculty appointment at an accredited research institution.
    1. The institution has agreed to provide adequate laboratory space necessary to perform the proposed research and adequate time (75% effort) to dedicate to research.
    1. The institution provides the candidate with an adequate and protected start-up package.

Phase Two: During phase two, applicants may request up to $325,000 USD per year (including 30% indirect costs) for up to five (5) years to support independent research.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.

(CLOSED) ADA Pathway to Stop Diabetes: Accelerator Awards

Slots: ADA will accept up to two (2) nominations per institution with one (1) nomination spanning basic through preclinical research and one (1) nomination spanning clinical through public health research. 

Each nomination can be for either of the Pathway Program Award types: Initiator or Accelerator. Please be aware that if an institution nominates two (2) applicants with proposed projects covering the same phase of research (i.e. basic through preclinical research studies), one of the submitted applications will be administratively disqualified from consideration for funding.

Deadlines

Internal Deadline: Friday, May 23rd, 2025, 5pm PT Closed.

LOI: N/A

External Deadline: Wednesday, July 23rd, 2025

Award Information

Award Type: Grant

Anticipated Award Amount: $325,000/year

Who May Serve as Applicant: Applicants must hold independent faculty positions and have demonstrated independent productivity in diabetes research. Applicants may currently hold independent NIH funding (K or R awards, including an initial NIH R01) but must not have applied for, or received, an NIH R01 renewal or a second R01 award.

Applicants must hold a MD, PhD, DMD, DO, PharmD, DVM or an equivalent health- or science-related degree.

Candidate’s must hold a full-time appointment at their sponsoring institution. Rare exceptions to full- time positions may be granted on a case-by-case basis and must be pre-approved by ADA Research Programs staff prior to application submission.

Applications are open to individuals with current research positions at university-affiliated institutions or other non-profit research institutions within the United States and U.S. possessions.

To assure continued excellence and diversity among applicants and awardees, the Association welcomes applications from all qualified individuals and strongly encourages applications from persons with diverse backgrounds, including minority groups that are underrepresented in biomedical

research.

Individuals must have permission to work within the U.S., either as U.S. citizens or permanent residents, or with appropriate work visas/permits. Institutional confirmation of permission to work within the U.S. will be required at the time of application submission.

Link to Award: https://professional.diabetes.org/research-grants/current-funding-opportunities-pathway-stop-diabetes

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

  • (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose

The Pathway to Stop Diabetes® Accelerator award is intended to provide flexible, long-term salary and research support to early career researchers who are proposing innovative and ambitious diabetes-related research programs, and who have distinguished themselves as exceptionally talented and promising research investigators.


These awards are highly competitive and intended to support particularly innovative and transformational ideas that have the potential to have an exceptional impact in diabetes with an emphasis on the investigator’s potential to significantly transform diabetes through research (‘moving the needle’) to improve the lives of people with diabetes.

Candidates for Accelerator awards should be in the process of establishing successful, independent diabetes research programs, and have records of independent productivity in research. For this award, demonstration of independent productivity should include that the candidate is currently in an independent faculty position, has demonstrated the ability to perform a particular set of experiments at a high-quality level, including senior author publications (independent of training mentors) and/or has demonstrated the ability to obtain independent funding/support for their work.

If funded, the Principal Investigator must agree to devote at least 75% of their total time and overall effort towards research. This percentage includes time dedicated to the Association-funded grant in addition to grants supported by other funding agencies. Please note that during the award’s duration, the Principal Investigator must commit between 25-50% effort towards the Association funded project.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.

(CLOSED) The Margaret E. Early Medical Research Trust Annual Grants Program – 2026

Slots: 8, including any renewal of existing grants from any one organization.

Deadlines

Internal Deadline: Friday, May 16th, 2025, 5pm PT Closed.

LOI: N/A

External Deadline: August 1, 2025, 5pm PT

Award Information

Award Type: Grant

Estimated Number of Awards: 8 – 10 (In a typical grant cycle, 2-3 grants are awarded to USC faculty).

Anticipated Award Amount: $75,000 over one year, including overhead. Note that the grant is twice renewable for up to $225,000 over three years.

Full RFP:

2026 General Application LetterDownload
2026 Application DirectionsDownload

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

  • (1) Two-Page Proposal Summary (1” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose

The Margaret E. Early Medical Research Trust is a qualified private foundation exempt from federal and state income taxes under the Internal Revenue Code Section 501(c)(3) and California Revenue and Taxation Code Section 23701(d). The Trust was created pursuant to the terms and provisions of the Last Will and Testament of Margaret E. Early, now deceased. The Trustee is authorized to select and fund in his sole and absolute discretion, research grant applications from qualified charitable organizations with substantial research facilities in the Los Angeles, California area conducting research into the causes, treatments, and potential cures of cancer and related diseases.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.

(CLOSED) NEA Grants for Arts 2025

Slots: An organization may submit only one application to the FY 2026 Grants for Arts Projects program (i.e., one application per calendar year).

Deadlines

Internal Deadline: Friday, May 9th, 2025, 5pm PT Contact RII.

Grants.gov Submission: July 10, 2025, 11:59pm ET

External Deadline: July 22, 2025, 11:59pm ET

Award Information

Award Type: Grant

Award Amount: Applicants may request an amount between $10,000-$100,000.

Local Arts Agencies only: Designated local arts agencies that are eligible to subgrant may request $30,000 to $150,000 for subgranting programs. See the Local Arts Agencies Application Instructions at the link to award below for more information on subgranting eligibility.

1:1 Cost-share/match required. Sources may include both cash and in-kind.

Link to Award: https://www.arts.gov/grants/grants-for-arts-projects

Who May Serve as PI: Organizations eligible to apply include:

  • Nonprofit, tax-exempt 501(c)(3), U.S. organizations;
  • Units of state or local government; or
  • Federally recognized tribal communities or tribes.

Applicant organizations must have completed at least 5 years of arts programming prior to the application deadline. Generally, an applicant may submit one application per calendar year.

Funding is not available in this category for individuals, applications submitted by a fiscal sponsor, or commercial/for-profit enterprises. 

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

  • (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.

Purpose

The NEA is committed to supporting excellent arts projects for the benefit of all Americans. Grants for Arts Projects (GAP) provides funding for public engagement with the arts and arts education, for the integration of the arts with strategies promoting the health and well-being of people and communities, and for the improvement of overall capacity and capabilities within the arts sector. We welcome applications from first-time and returning applicants; from organizations serving rural, urban, suburban, and tribal communities of all sizes; and from organizations with small, medium, or large operating budgets.

We fund arts projects in the following disciplines: Artist Communities, Arts Education, Dance, Design, Film & Media Arts, Folk & Traditional Arts, Literary Arts, Local Arts Agencies, Museums, Music, Musical Theater, Opera, Presenting & Multidisciplinary Works, Theater, and Visual Arts.

A full grant program description can be found under Grant Program Details at the link posted above. For detailed instructions on how to apply, see Application Instructions also at the link posted above.

The Conservation, Food & Health Foundation 2026 Grants

Slots: 1. The Foundation will consider only one proposal from an organization in any calendar year.

Deadlines

Internal Deadline: Friday, May 9th, 2025, 5pm PT Contact RII.

LOI: June 15, 2025

External Deadline: August 15, 2025

Award Information

Award Type: Grant

Anticipated Award Amount: It is anticipated that most grants will fall in the $25,000-$50,000 per year range.

Eligible Applicants:

The Foundation supports local, state, and regional organizations in Africa, Asia, the Caribbean, Latin America, and the Middle East in the countries where the projects are based.  It also supports organizations located in upper-income countries working with local partners in these areas.  It does not support projects in post-Soviet states or Balkan states.

Most types of organizations that can provide evidence of their non-governmental status or charitable purpose are eligible to apply, including non-governmental organizations, nonprofit organizations; civil society organizations; community-based organizations; and colleges, universities, and other academic institutions.

Government agencies and religious organizations may be included as project partners but are not eligible for direct funding.

The Foundation does not typically fund:

  • Overhead or indirect project costs
  • General operating support
  • Direct food, health or other humanitarian aid
  • Eco-tourism
  • Buildings and capital improvements
  • Projects ultimately intended for private gain.  All intellectual property developed with the grant should be public.
  • Salaries for Executive Directors of U.S. and European-based organizations.
  • Project expenses incurred before the grant is awarded.

Link to Award: https://cfhfoundation.grantsmanagement08.com/

Process for Limited Submissions

PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template

Materials to submit include:

  • (1) Two-Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
  • (2) CV – (5 pages maximum)

Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.

Purpose

The Conservation, Food and Health Foundation seeks to protect the environment, improve food production, and promote public health in Africa, Asia, the Caribbean, Latin America, and the Middle East. 

Types of Support

The Foundation supports projects and applied research that:

  • Generate local or regional solutions to problems affecting the quality of the environment and human life;
  • Advance local leadership and promote professional development in the conservation, agricultural, and health sciences;
  • Develop the capacity of local organizations and coalitions; and
  • Address challenges in the field. 

The Foundation prefers to support projects that address under-funded issues and geographic areas.

The Foundation funds applied research, pilot projects, new initiatives, training, and technical assistance, rather than ongoing support for programs that are already well underway.  An important goal for the Foundation is to provide seed money to help promising projects, organizations, and individuals develop the track record they need to attract major foundation funding in the future.

Fields of Interest

The following are examples of the Foundation’s areas of interest within the fields of conservation, food, and health, and are not meant to be exclusive.

Conservation

Conservation grants promote environmental conservation through field research, projects, and advocacy that:

  • Protect biodiversity and preserve natural resources.
  • Help mitigate the adverse effects of climate change.
  • Build the scientific and technical capacity of local conservation organizations and promote local, regional, and international partnerships.
  • Increase engagement between scientists, local communities and organizations, and decision-makers.
  • Partner with indigenous communities and local people.

Food

Grants in the food and agriculture program area focus on research-based projects that build capacity for self-sufficiency and resilience to climate change, strengthen local food systems, and support healthy nutrition through projects that: 

  • Enhance food security.
  • Develop and promote sustainable agricultural practices
  • Build the capacity of small-scale farmers.
  • Advance farmer research and research partnerships.
  • Develop environmentally sound and affordable approaches to control pests and diseases affecting important local food crops.
  • Promote indigenous food sovereignty and knowledge systems.
  • Address challenges of uptake and scalability through new methods of extension, education, and technology transfer.

Health

The Foundation supports efforts that test new ideas and approaches that promote public health, with a special emphasis on reproductive health and family planning and their integration with other health promotion activities.  It favors community-level disease prevention and health promotion projects and efforts that help strengthen regional and country public health systems over disease diagnosis, treatment, and care provided by clinics, hospitals, and humanitarian aid programs.

Activities that help increase capacity include applied research, program development, technical assistance, and training projects that:

  • Promote reproductive health and family planning.
  • Address issues related to mental and behavioral health.
  • Address issues relating to pollution and environmental health.
  • Increase the understanding of zoonotic and neglected tropical diseases.
  • Address issues relating to nutrition and health.

Key Priorities

In all of its areas of interest, the Foundation gives priority to projects that have the potential to advance the field, build local capacity, promote replication, influence public opinion and policy, affect systems change, and benefit people beyond the immediate project and its local context.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.

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