Slots: 2 slots taken.
Deadlines
Internal Deadline: Friday, May 31st, 2024, 5pm PT Closed.
LOI: August 6, 2024
External Deadline: September 6, 2024
Award Information
Award Type: Grant
Estimated Number of Awards: 12-13
Anticipated Award Amount: Awards will be for up to $250,000 in Direct Costs per year, plus applicable Facilities and Administrative (F&A) costs.
Who May Serve as PI:
- Single PD/PI: Only single PD/PI applications are allowed. Multiple PD/PIs applications will not be accepted. Only the PD/PI may be listed as a Senior/Key Person and provide a Biographical Sketch.
- Citizenship: U.S. citizenship is not required. For non-U.S. citizens, the applicant institution is responsible for ensuring the PD/PI’s U.S. visa status will allow them to conduct the proposed research at the applicant institution for the entire project period.
- Degree Receipt Date: The receipt date of the PD/PI’s terminal doctoral degree or end of post-graduate clinical training must be between May 1, 2023, and September 30, 2025. The degree receipt date is that which appears on the official transcript for the degree. The end of post-graduate clinical training includes residency and fellowship periods. At the time of award, either:
- The PD/PI must have received a PhD, MD, DO, DC, DDS, DVM, OD, DPM, ScD, EngD, DrPH, DNSc, ND (Doctor of Naturopathy), PharmD, DSW, PsyD, or equivalent doctoral degree from an accredited domestic or foreign institution (it is the responsibility of the sponsoring institution to determine if a foreign doctoral degree is equivalent).
- Or an authorized official of the degree-granting or training institution must certify that all degree requirements have been met and that the receipt date of the degree (as will appear on the transcript) will be before September 30, 2025. An authorized official of the host institution must certify that the PD/PI will be able to conduct independent research at the institution at the time of the project start date.
- Post-doctoral Experience: The PD/PI must not have served as a post-doctoral fellow for more than 12 months following a previous, non-terminal doctoral degree (this only applies to PD/PIs with multiple doctoral degrees who served in a 12+ month post-doctoral fellowship before their terminal degree).
- Level of Effort: In the first and second years of the project period, the PD/PI must commit at least 9.6 person-months of effort to the Early Independence Award project each year (80% effort per year). In years 3-5 of the project period, the PD/PI may reduce their effort on the Early Independence Award project but must still conduct at least 9.6 person-months of general independent research each year (80% effort per year). General independent research includes the effort spent on the Early Independence Award project and any other independent research projects the PD/PI is working on.
- Non-independence at Time of Application: Individuals are eligible only if they do not have research independence at the time of application submission. Research non-independence is defined functionally rather than by position title and must have all the following characteristics:
- The PD/PI’s current research agenda is set through concurrence with mentors.
- The PD/PI’s research is funded primarily through support to other investigators (mentored fellowships such as NIH F31 or F32 Fellowships or NSF Graduate Research Fellowships do not preclude eligibility).
- The PD/PI does not have any space assigned directly by the institution for the conduct of their research.
- The PD/PI cannot apply for an NIH R01 grant without a special waiver or exemption from the institution according to institutional policy.
Though PD/PIs must not be functionally independent at the time of application submission, they may become functionally independent prior to time of award and still retain eligibility.
- Independent Research Position: An independent research position at a host institution is required, and the PD/PI must be able to begin independent research by the project start date. The position need not be permanent or tenure-track and may be contingent upon receipt of the Early Independence Award. Prospective PD/PIs should contact appropriate institutional leaders to seek an appointment to an independent research position. Alternatively, institutions may actively recruit eligible scientists to apply for support through this initiative. In either case, the institution is expected to provide substantial support to the PD/PI as detailed in the Facilities & Other Resources section. To foster independence, PD/PIs may benefit from being hosted by an institution at which they have not previously studied or trained.
- Career Awards: PD/PIs may apply for a research career development (K) award and DP5 at the same time, but NIH policy prohibits scientific overlap. A PD/PI may not hold a DP5 and career development award concurrently: The career development award must be relinquished to receive the DP5.
- Site Visit: NIH staff will conduct a one-time site visit at the end of the first year to assess the PD/PI’s progress and to ensure they are receiving the institutional resources and support outlined in the application. NIH staff will meet with the PD/PI, lab personnel, mentors, faculty, and institutional leadership. Failure to provide independence and/or support may lead to NIH actions, including reduction of funds.
Link to Award: https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-24-005.html
Process for Limited Submissions
PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template
Materials to submit include:
- (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
- (2) CV – (5 pages maximum)
Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.
Purpose
The NIH Director’s Early Independence Award provides an opportunity for promising, newly graduated scientists to accelerate their entry into an independent research career by forgoing the traditional post-doctoral training period. Though most newly graduated doctoral-level researchers would benefit from post-doctoral training, a small number of capable investigators are ready to launch independent research careers. The Early Independence Award is intended for these select investigators, who have already established a record of scientific innovation and research productivity and have demonstrated unusual scientific vision and maturity. Typical post-doctoral training would unnecessarily delay their entry into independent research. The award also provides an opportunity for institutions to invigorate their research programs by bringing in fresh scientific perspectives of the awardees they host.
The Early Independence Award assists the transition to independence by supporting research projects at host institutions that provide independent research positions for newly graduated scientists. To be eligible, investigators must complete their terminal doctoral degree or clinical training sometime between May 1, 2023, and September 30, 2025. To be consistent with the NIH definition of Early Stage Investigators, eligible clinical training includes clinical residency and clinical fellowship (see Section III. Eligibility Information for more information). By the end of the award period, Early Independence Award investigators are expected to be competitive for continued funding of their research program through other NIH funding activities and for permanent research-oriented positions.
To support innovative and novel research across the NIH mission, the NIH recognizes the need to foster a diverse research workforce across the nation. Talented researchers from diverse backgrounds (including individuals from underrepresented racial and ethnic groups, individuals with disabilities, individuals from disadvantaged backgrounds, and women; see Notice of NIH’s Interest in Diversity), are strongly encouraged to work with their institutions to develop applications for this funding opportunity. As outstanding research is conducted at a broad spectrum of institutions, applications from the full range of eligible institutions (including institutions that provide services to underrepresented or underserved communities, those that may be less research-intensive, and from all domestic geographic locations) are encouraged to apply. Applications are welcome in all research areas broadly relevant to the mission of NIH. These areas include, but are not limited to, the behavioral, medical, natural, social, applied, and formal sciences. Research may be basic, translational, or clinical. The primary requirements are that the research be highly innovative and have the potential for broad impact.
Prospective applicants are invited to a pre-application webinar on June 26, 2024, from 1:00-2:30 PM EDT. NIH staff will discuss the initiative and answer questions about the application and review process. Questions for the webinar should be submitted ahead of time to EarlyIndependence@od.nih.gov by 11:59 PM local time on June 21, 2024. Additional questions may be taken during the webinar if time allows. Register for the webinar and join on Webex. The webinar will be recorded and posted on the Early Independence Award website.
The NIH Director’s Early Independence Award is part of the High-Risk, High-Reward Research program funded through the NIH Common Fund, which supports cross-cutting programs that are expected to have exceptionally high impact. All Common Fund initiatives invite investigators to develop bold, innovative, and often risky approaches to address problems that may seem intractable or to seize new opportunities that offer the potential for rapid progress.
Visit our Institutionally Limited Submission webpage for more updates and other announcements.