University Park Campus

Dynamic Imaging Science Center

The mission of the Dynamic Imaging Science Center (DISC) is to better understand the science of human movement in health and disease, through the development and use of non-invasive imaging. The facility operates a high-performance 0.55 Tesla whole-body MRI scanner, with a wide range of physiological monitoring systems that can be utilized simultaneously with imaging. Current projects include the imaging of the upper airway vocal tract during speech production, swallowing, and sleep; imaging movement of joints such as the wrist; and cardio-pulmonary imaging.

Equipment and services include: The Center will provide MRI scan time on a 0.55 Tesla low-field scanner (billed hourly). We will also provide MRI data archiving and retrieval for raw data and reconstructed images. This will be billed per scan, and by Gigabyte for unusually large datasets. MRI, magnetic resonance imaging, low field, scanner, data archival.

University Park Campus
MCB LL130
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Center for Peptide and Protein Engineering

The USC Center for Peptide and Protein Engineering (CPPE) aims to put USC in a position of undisputed leadership in peptide and protein science by creating functional peptides and proteins as imaging agents, diagnostics and therapies. This core laboratory will be housed in the new Michelson Center for Convergent Biosciences and serve the USC Community to generate new peptide and protein tools. New technology advances in several fields now provide the foundation for high-throughput molecular engineering—creating new peptides and antibody-like proteins that bind specific targets on a genomic scale.

Equipment and services include: A la carte and comprehensive peptide synthesis and purification services for the USC and general community. End-to-end production of peptides includes: assistance in peptide design, Fmoc-based solid-phase peptide synthesis, peptide purification, conformation of peptide identity by mass spectrometry, and assessment of purity by reverse-phase HPLC. Peptide synthesis is performed on a Biotage Syro I Multi-Peptide Synthesizer (supported by a grant from the USC Core Instrumentation Fund) at 50 μmol scale up to 20 amino acids. Peptide purification is performed via Biotage reverse-phase flash chromatography and/or reverse-phase HPLC chromatography using Agilent HPLC and LCMS equipment.

2nd floor
USC Michelson Center for Convergent Bioscience
MCB 267

Website

Schaeffer Center Data Core

The Schaeffer Data Core’s mission is to improve the quality and productivity of research related to health economics and policy through organized data resources, training, and the expertise of its staff.

Services include: comprehensive data library, analytic computing environments, data and programming expertise, and protected data management.

University Park Campus
USC Schaeffer Center
635 Downey Way VPD
Los Angeles, CA 90089-3333
Website

Nanobiophysics Core

The Center of Excellence in NanoBiophysics supports faculty and students across the university in the study of molecular nano-assembly, structures and functions. Housed in the Dornsife College, the Center is used by research programs in structural biology, nanotechnology, anomedicine, molecular biology, biochemistry, and materials sciences.

3616 Trousdale Parkway
AHF B15
Los Angeles, CA 90089

Website

Shoah Foundation

The Shoah Foundation’s mission is to develop empathy, understanding, and respect through testimony. The Institute currently has more than 55,000 video testimonies, each one a unique source of insight and knowledge that oﬀers powerful stories from history that demand to be explored and shared. The testimonies are preserved in the Visual History Archive, one of the largest digital collections of its kind in the world. They average a little over two hours each in length and were conducted in 65 countries and 43 languages. The vast majority of the testimonies contain a complete personal history of life before, during, and after the interviewee’s firsthand experience with genocide.

650 West 35th Street, Suite 401
Los Angeles, California

Website

X-Ray Crystallography Facility

The purpose of the X-Ray Crystallography Facility is to structurally characterize single-crystal samples of organic, inorganic, and organometallic compounds using X-ray diffraction. Equipment and services include: a Bruker APEX DUO single-crystal diffractometer equipped with an APEX2 CCD detector, Mo fine-focus and Cu micro-focus X-ray sources and a Rigaku Ultima IV powder/thin film diffractometer to conduct rapid structural analysis. It is capable of handling samples that are sensitive to air, moisture, and/or temperature and the core provides training for users to conduct their own experiments.

University Park Campus
John Stauffer Science Lecture
837 Bloom Walk
Los Angeles, CA 90087