Slots: Only one application per UM1 applicant institution is allowed. New applications that are not submitted as part of the companion and required UM1 PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional) will be considered as not responsive.
Deadlines
Internal Deadline: Monday, March 18th, 2024 Contact RII.
LOI: N/A
External Deadline: May 17, 2024
Recurring Deadlines: September 13, 2024
Award Information
Award Type: Grant
Estimated Number of Awards: The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Anticipated Award Amount: The maximum budget is $100,000 direct costs/year. The budget request for a given application needs to be adequately justified and reflect the actual needs of the proposed project. Yearly fluctuations in the project workload should be reflected in the requested budget.
Who May Serve as PI: Researchers from diverse backgrounds, including racial and ethnic minorities, persons with disabilities, and women are encouraged to participate as preceptors/mentors. Mentors should have research expertise and experience relevant to the proposed program. Mentors must be committed to continue their involvement throughout the total period of the mentee’s participation in this award.
Link to Award: https://grants.nih.gov/grants/guide/pa-files/PAR-21-339.html
Process for Limited Submissions
PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template
Materials to submit include:
- (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
- (2) CV – (5 pages maximum)
Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.
Purpose
The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers. The overarching goals of the NIH R25 program are to: (1) complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs; (2) encourage individuals from diverse backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences, to pursue further studies or careers in research; (3) help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences; and (4) foster a better understanding of biomedical, behavioral and clinical research and its implications.
The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs.
The overarching goal of this R25 program is to provide support to recipients of Clinical and Translational Science Awards (CTSA) for research experiencess that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. To accomplish this over-arching goal, this FOA will support creative educational activities with a primary focus on:
- Research Experiences:
- Research experiences are expected to be relevant to NCATS mission of studying translation on a system-wide level, agnostic to a specific disease, to better understand the scientific and operational principles underlying each step of the translational process. The goal is not to focus on specific diseases, but on what is common among them and the translational science process. Examples of research experiences appropriate for career levels include, but are not limited to:
- Undergraduates: to provide hands-on exposure to research that reinforces their interest in clinical and translational science and/or prepares them for graduate school matriculation and/or careers in clinical and translational science for graduate and medical, dental, nursing and other health professional students.
- Postdoctoral Fellows and Medical Residents: to extend their skills, experiences, and knowledge base in order to engage in clinical and translational science research activities.
- Junior Faculty: to enhance their research skills, experiences, and knowledge base relative to clinical and translational science by working with faculty members at a partnering institution.
- Research experiences are expected to be relevant to NCATS mission of studying translation on a system-wide level, agnostic to a specific disease, to better understand the scientific and operational principles underlying each step of the translational process. The goal is not to focus on specific diseases, but on what is common among them and the translational science process. Examples of research experiences appropriate for career levels include, but are not limited to:
- Proposed research experiences should involve an innovative approach to provide hands-on exposure to clinical and translational science research in a laboratory or a field setting for a full-time (40 hours per week) period of 10 to 15 weeks in order to stimulate the interest and advance the knowledge base of participants to consider further education and training for future careers as clinical and translational science researchers. The proposed programs should provide research experiences that are not available through formal NIH training mechanisms.R25 programs that propose at least 10 weeks, but fewer than 15 weeks, of full-time research experiences are allowed to request continued part-time support for the participants to work on their research projects, up to the equivalent of 15 weeks of full-time participation, as long as the entire research experience is completed within a 12-month period. Successful participants may be appointed for additional periods of short-term research experiences.
Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving Federal support. R25 programs may augment institutional research training programs (e.g., T32, T90) but cannot be used to replace or circumvent Ruth L. Kirschstein National Research Service Award (NRSA) programs.
Background
The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH), is transforming the translational science process so that new treatments and cures for disease can be delivered to patients faster. NCATS strives to develop innovations to reduce, remove or bypass costly and time-consuming bottlenecks in the translational research pipeline in an effort to speed the delivery of new drugs, diagnostics and medical devices to patients. Translation is the process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public from diagnostics and therapeutics to medical procedures and behavioral changes. Translational science is the field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process. NCATS studies translation on a system-wide level as a scientific and operational problem. The NCATS approach is not to focus on specific diseases, but on what is common among them and the translational science process. NCATS does this by developing new approaches, technologies, resources and models; demonstrating their usefulness; and disseminating the data, analysis and methodologies to the community.
The goal of the NCATS Clinical and Translational Science Awards (CTSA) Program is to develop innovative solutions that will improve the efficiency, quality and impact of the process for turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public. Sustaining a vibrant clinical and translational research enterprise requires a 21st century workforce that can advance clinical and translational science that will, in turn, increase the efficiency and efficacy of translation with the ultimate goal of getting more treatments to more patients more quickly.
Examples of research experiences include:
- Research experiences centered on the conduct of translational science research. Participants should be exposed to the spectrum that represents each stage of translational science research that includes the path from the biological basis of health and disease to interventions that improve the health of individuals and the public https://ncats.nih.gov/translation/spectrum.
- Providing research experiences within and outside of academia (e.g., industry, regulatory agency, nonprofit patient-advocacy group) beyond the home CTSA hub.
- Research experiences focused on entrepreneurship and commercialization that broaden the impact of scientific findings beyond the laboratory.
- Support research experiences for participants from less research-intensive partner institutions to gain clinical and translational science research experiences.
- Support faculty from less research-intensive partner institutions to gain research experiences on improving instruction and mentoring capacity in clinical and translational science at their home institutions.
Applications Not Responsive to this FOA
The following types of applications will be deemed nonresponsive and will not be reviewed:
- New applications that are not submitted concurrently with the required UM1 (PAR-21-293: Clinical and Translational Science Award).
- Applications that do not meet the criteria noted under the eligibility criteria (see Section III).
- Applications that do not submit all of the required attachments.
- Resubmitted R25 applications that are not linked to a funded UM1.
Visit our Institutionally Limited Submission webpage for more updates and other announcements.