Translational Research and Clinical Trials

High throughput screening and liquid handling core

The High Throughput Screening and Liquid Handling (HTS) Core is equipped with advanced automation platforms, including the Echo 650 and Biomek i5 (Beckman), integrated with a centrifuge, temperature controller, and mixer. These systems enable fully automated, high-throughput small molecule screening and liquid handling.

The HTS Core maintains in-house compound libraries comprising:

FDA-approved drugs
Epigenetic modulators
Preclinical compounds
Nucleoside analogs

We support translational research for all USC schools, with a focus on therapeutic development and therapeutic target validation. Our services include: 1) High throughput drug screen, 2) Automated and contactless drug dispensing, 3) High-throughput liquid handling for molecular biology applications; and 4) Assay development and optimization.

Health Sciences Campus
USC Norris Cancer Center
1440 Biggy Street., NOR5838
Los Angeles, CA 90033

Website: https://sites.usc.edu/hts/

Keck Genomic Platform

The Keck Genomics Platform (KGP CORE) provides high-throughput industry-standard next-generation sequencing services to the University of Southern California and its collaborators. KGP utilizes Illumina high-throughput next generation sequencers, such as NovaSeq 6000 and Miseq, to offer comprehensive data analysis, customized pipelines, and secure data management. KGP allows for collaborative research and genomic innovation offering comprehensive services from sample processing to data analysis.

Keck School

1975 Zonal Ave.

Los Angeles, CA 90033

323-442-1100

Website

Schaeffer Center Data Core

The Schaeffer Data Core’s mission is to improve the quality and productivity of research related to health economics and policy through organized data resources, training, and the expertise of its staff.

Services include: comprehensive data library, analytic computing environments, data and programming expertise, and protected data management.

University Park Campus
USC Schaeffer Center
635 Downey Way VPD
Los Angeles, CA 90089-3333
Website

SC CTSI-Southern California Clinical and Translational Science Institute

Welcome to the Southern California Clinical and Translational Science Institute (SC CTSI), a multifaceted resource for clinical and community-partnered translational research. Set in the urban heart of Los Angeles where 85% of residents are from minority groups, 90 languages are spoken, and disease burden is high, we support researchers who face special challenges above and beyond traditional research hurdles. We view these challenges as opportunities to make research with diverse populations easier and more beneficial for our communities.

University of Southern California
2250 Alcazar Street, CSC 200
Los Angeles, CA 90033
Website

Clinical Trials Unit (CTU)

The Clinical Trials Unit (CTU) “is a one-stop shop with highly qualified personnel and offers a broad range of services for investigators to conduct study visits ranging low complexity to high complexity.”

University of Southern California
2250 Alcazar Street, CSC 200
Los Angeles, CA 90033
Website

Translational Research Laboratory

The core mission of the USC Mann School of Pharmacy Translational Research Laboratory (TRLab), located in 13laboratory spaces of the Pharmaceutical Sciences Center, has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the Mann School of Pharmacy and at USC.

Equipment and services include: The TRLab is equipped with over 80 specialized instruments in the applications of: 1) Sample Processing, 2) Cell and Immunobiology, 3) Flow Cytometry, 4) Imaging, 5) Molecular Analysis, 6) Molecular Biology and 7) RNA/DNA Sequencing.

Health Sciences Campus
Pharmaceutical Sciences Center
Website