Imaging

Translational Research Laboratory

The core mission of the USC Mann School of Pharmacy Translational Research Laboratory (TRLab), located in 13laboratory spaces of the Pharmaceutical Sciences Center, has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the Mann School of Pharmacy and at USC.

Equipment and services include: The TRLab is equipped with over 80 specialized instruments in the applications of: 1) Sample Processing, 2) Cell and Immunobiology, 3) Flow Cytometry, 4) Imaging, 5) Molecular Analysis, 6) Molecular Biology and 7) RNA/DNA Sequencing.

Health Sciences Campus
Pharmaceutical Sciences Center
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Optical Imaging Facility

The Optical Imaging Facility specializes in cellular and subcellular fixed or dynamic imaging and analysis of biological material. The facility provides access to powerful microscopes that enable scientists to take high-resolution pictures of stem cells. These include still images and time-lapse videos. Cells or parts of cells can be labeled with fluorescent dyes, which enable better identification of molecules and structures within cells, or to trace the fate of cells as they migrate, divide and differentiate within tissues.

Health Sciences Campus
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC
1425 San Pablo Street, BCC 212
Los Angeles, CA 90033
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Neuroplasticity and Imaging

Research at the Neuroplasticity and Imaging Lab uses Transcranial Magnetic Stimulation (TMS) to investigate brain-behavior relationships during motor skill learning and motor control in non-disabled and brain-injured individuals. Equipment and services include: the lab maintains a range of TMS technologies for research use (Magnetic stimulation system, Magstim 2002, Bistim2, Magstim Rapid2, 2nd Generation Remote Coils, Custom Coils, Double 70mm Cooled Coil System, Brain navigation system, EMG recording system, DataWizard).

Health Sciences Campus
Center for Health Professions
1540 Alcazar Street, CHP 155
Los Angeles, CA 90089-9006
Website

Research Imaging Core at the Saban Research Institute

The Research Imaging Core at the Saban Research Institute, CHLA, is a full-service in vivo imaging laboratory providing non-invasive capabilities for use on mammalian models. Equipment & services include: data collection, processing and interpretation and access to core instrumentation: a Xenogen for optical imaging (bioluminescence and fluorescence), a 7T micro Magnetic Resonance Imager (MRI), a micro X-ray Computed Tomography (CT) instrument and a Gamma Medica combined CT micro Single Photon Emission Computed Tomography (SPECT).

Children’s Hospital Los Angeles, CHLA
Saban Institute Small Animal Imaging Research Center
4661 Sunset Blvd.
Los Angeles, CA 90027

Cellular Imaging Core

The Cellular Imaging Core houses light microscopy and digital image processing equipment to support cell biology research.

Services include: consultation on the design, execution, and analysis of fixed and live cell imaging experiments as well as training in the utilization of Core facilities.

Equipment includes: Lightsheet microscope (LaVision Biotec Ultramicroscope II), laser scanning confocal microscopes (Zeiss LSM 710 & 700), live cell imaging microscope and spinning disk confocal (BD/CrEST CARVII) with temperature/CO2/O2 control, widefield fluorescence microscopes (Leica DMI6000B AFC & Nikon Eclipse Ti-E), Optical Projection Tomography (OPT) microscope, 3D image rendering and analysis workstation with Arivis Vision4D and AutoQuant deconvolution software, 2D image analysis workstation with MetaMorph software.

Children’s Hospital Los Angeles, CHLA
Smith Research Tower
4546 Sunset Blvd
Los Angeles, CA 90027
Website

Multi-Photon Microscopy Core

The Multi-Photon Microscopy Core provides in vivo imaging of intact organs in small animals with high temporal and subcellular resolution, ideal for studying (patho)physiological processes in health and disease.

Equipment includes: a Leica TCS SP5 AOBS Multi-Photon Confocal Microscope System.

Health Sciences Campus
Zilkha Neurogenetic Institute
1501 San Pablo Street, ZNI 313
Los Angeles, CA 90089
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