Slots: 1
Deadlines
Internal Deadline: Wednesday, January 8th, 2025, 5pm PT Contact RII.
LOI: January 19, 2025
External Deadline: February 19, 2025
Award Information
Award Type: Cooperative Agreement
Estimated Number of Awards: 1
Anticipated Award Amount: $4,800,000
Who May Serve as PI: Standard CDC language.
Link to Award: https://www.grants.gov/search-results-detail/355903
Process for Limited Submissions
PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/. Use the template provided here: RII Limited Submission Applicant Template
Materials to submit include:
- (1) Two-Page Proposal Summary (1” margins; single-spaced; standard font type, e.g. Arial, Helvetica, Times New Roman, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 2-page limit will be excluded from review. You must use the template linked above.
- (2) CV – (5 pages maximum)
Note: The portal requires information about the PIs in addition to department and contact information, including the 10-digit USC ID#. Please have this material prepared before beginning this application.
Purpose
The purpose of this Notice of Funding Opportunity (NOFO) is to support the implementation and evaluation of effective strategies for incorporating a postexposure prophylaxis-in-pocket (PiP) approach into existing preexposure prophylaxis (PrEP) services. This effort aims to prevent HIV and sexually transmitted infections (STIs) among disproportionately affected populations, for example, men who have sex with men (MSM) and transgender women (TGW).
The PiP approach is designed to enhance access to nonoccupational postexposure prophylaxis (nPEP) for HIV prevention. nPEP is a critical intervention for use after a potential HIV exposure but is often underused due to challenges in accessing timely healthcare. PiP addresses this issue by providing individuals with a supply of nPEP medication and related resources, enabling immediate prevention following a potential HIV exposure.
This research study will focus on implementing and evaluating the integration of PiP “PEP packs” into existing PrEP and STI clinical services. These PEP packs will contain antiretroviral medications for HIV nPEP, doxycycline for STI postexposure prophylaxis (DoxyPEP), HIV and STI self-test kits, and instructional materials. The study aims to increase access to nPEP by providing medication starter packs for immediate use after known or potential HIV or STI exposure and ensuring access to clinical follow-up after nPEP initiation.
The intervention should be conducted in clinical settings that serve communities with high rates of HIV diagnoses among disproportionately affected populations, e.g., Black/African American (Black) and Hispanic/Latino (Hispanic) MSM and TGW. If successful, this approach would enhance HIV and STI prevention among populations, including disproportionately affected populations, leading to more equitable health outcome. This NOFO, including funding and eligibility, is not limited based on, and does not discriminate on the basis of race, color, national origin, disability, age, sex (including gender identity, sexual orientation, and pregnancy) or other constitutionally protected statuses.
Visit our Institutionally Limited Submission webpage for more updates and other announcements.