Internal Deadline: Contact RII.
External Deadline: February 23, 2023
Award Type: Cooperative Agreement
Estimated Number of Awards: 3
Anticipated Award Amount: $7,500,000
Who May Serve as PI: Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work with his/her
organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for HHS/CDC support.
Process for Limited Submissions
PIs must submit their application as a Limited Submission through the Research Initiatives and Infrastructure (RII) Application Portal: https://rii.usc.edu/oor-portal/.
Materials to submit include:
- (1) Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.
- (2) CV – (5 pages maximum)
Note: The portal requires information about the PIs and Co-PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.
CDC supports efforts to improve the health of populations disproportionately affected by
infectious diseases by maximizing the health impact of public health services, reducing disease
incidence, and advancing health equity.
A health disparity occurs when a health outcome is seen to a greater or lesser extent between
populations. Health disparities in infectious diseases are inextricably linked to a complex blend
of social determinants that influence which populations are most disproportionately affected by
these infections and diseases.
Social determinants are conditions in the places where people live, learn, work, and play that
affect a wide range of health and quality-of life-risks and outcomes
(https://www.cdc.gov/socialdeterminants/index.htm). These include conditions for early
childhood development; education, employment, and work; food security, health services,
housing, income, and social exclusion. Health equity is a desirable goal that entails special
efforts to improve the health of those who have experienced social or economic challenges. It
Continuous efforts focused on elimination of health disparities, including disparities in
health and in the living and working conditions that influence health, and
Continuous efforts to maintain a desired state of equity after health disparities are
Applicants should use data, including social determinants data, to identify communities within
their jurisdictions that are disproportionately affected by infectious diseases and related diseases
and conditions, and plan activities to help eliminate health disparities. In collaboration with
partners and appropriate sectors of the community, applicants should consider social
determinants of health in the development, implementation, and evaluation of specific efforts and
use culturally appropriate interventions and strategies that are tailored for the communities for
which they are intended.
Healthy People 2030 and other National Strategic Priorities
Several Healthy People 2030 objectives are supported through this NOFO:
HIV-1 Reduce the number of new HIV diagnoses among adolescents and adults
Increase knowledge of HIV status
HIV-2 Increase the proportion of persons who know their HIV status
HIV-3 Reduce the number of new HIV diagnoses
HIV-4 Increase the proportion of persons aged 13 years and over with newly diagnosed
HIV infection linked to HIV medical care within 1 month
Increase HIV testing and prevent HIV risk
HIV-13 Increase the proportion of persons with HIV who know their serostatus
HIV-17 Increase the proportion of sexually active persons who use condoms
HIV-19 Increase the percentage of persons with newly diagnosed HIV infection linked to
SDOH-R01 Increase the proportion of federal data sources that collect country of birth as
PHI-R07 Explore the use and impact of quality improvement as a means for increasing
efficiency and/or effectiveness outcomes in health departments
This NOFO also supports HIV National Strategic Plan (2022-2025) goals.
Goal 1: Prevent New HIV Infections
1.3.4 Implement culturally competent and linguistically appropriate models and other
innovative approaches for delivering HIV prevention services.
1.3.5 Support research into the development and evaluation of new HIV prevention
modalities and interventions for preventing HIV transmissions in priority populations.
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1.3.6 Expand implementation research to successfully adapt evidence-based interventions
to local environments to maximize potential for uptake and sustainability.
Goal 3: Reduce HIV-Related Disparities and Health Inequities
3.1.1 Strengthen enforcement of civil rights laws (including language access services and
disability rights), promote reform of state HIV criminalization laws, and assist states in
protecting people with HIV from violence, retaliation, and discrimination associated with
HIV status, homophobia, transphobia, xenophobia, racism, substance use, and sexism.
3.1.2 Ensure that health care professionals and front-line staff complete education and
training on stigma, discrimination, and unrecognized bias toward populations with or
who experience risk for HIV, including LGBTQI+ people, immigrants, people who use
drugs, and people involved in sex work.
3.1.3 Support communities in efforts to address misconceptions and reduce HIV-related
stigma and other stigmas that negatively affect HIV outcomes.
3.1.4 Ensure resources are focused on the communities and populations where the need is
greatest, especially Black, Latino, and American Indian/Alaska Native and other people
of color, particularly those who are also gay and bisexual men, transgender people,
people who use substances, sex workers, and immigrants.
3.1.5 Create funding opportunities that specifically address social and structural drivers
of health as they relate to Black, Latino, and American Indian/Alaska Native and other
people of color.
3.4.4 Develop and implement effective, evidence-based, and evidence-informed
interventions that address social and structural determinants of health among people with
or who experience risk for HIV including lack of continuous health care coverage, HIVrelated stigma and discrimination in public health and health care systems, medical
mistrust, inadequate housing and transportation, food insecurity, unemployment, low
health literacy, and involvement with the justice system.
3.5 Expand effective communication strategies between providers and consumers to build
trust, optimize collaborative decision-making, and promote success of evidence-based
prevention and treatment strategies.
Visit our Institutionally Limited Submission webpage for more updates and other announcements.